Accuracy of intraoral scan with prefabricated aids and stereophotogrammetry compared with open tray impressions for complete-arch implant-supported prosthesis: A clinical study.

OBJECTIVES: The aim of this clinical study was to compare the accuracy of intraoral scan system (IOS) with prefabricated aids and stereophotogrammetry (SPG) compared with open tray implant impression (OI) for complete-arch implant-supported fixed dental prostheses (CIFDP). MATERIALS AND METHODS: Patients needing CIFDP were enrolled in this study. OI, reference standard, IOS with prefabricated aids, and SPG were performed for each patient. Distance and angle deviations between all pairs of abutment analogs, root mean square (RMS) errors between the aligned test and reference model, and chairside time were measured. The effect of inter-abutment distance, jaw (maxilla or mandible), number of implants, and arch length on deviations was analyzed. The mixed effect model was applied to analyze deviations and RMS errors. RESULTS: Fifteen consecutive individuals (6 females and 9 males, 47-77 years old) with 22 arches (9 upper and 13 lower jaws) and 115 implants were included. There was no significant difference in distance deviation comparing SPG and IOS with OI (p > .05). IOS showed a significantly greater angle deviation and RMS errors than SPG (median 0.40° vs. 0.31°, 69 µm vs. 45 µm, p < .01). The inter-abutment distance was negatively correlated with the accuracy of SPG and IOS (p < .05). The chairside time for IOS, SPG, and OI was 10.49 ± 3.50, 14.71 ± 2.86, and 20.20 ± 3.01 min, respectively (p < .01). CONCLUSIONS: The accuracy of SPG and IOS with prefabricated aids was comparable. IOS was the most efficient workflow.

Efficient Fe3C-CF Cathode Catalyst Based on the Formation/Decomposition of Li2-xO2 for Li-O2 Batteries.

Lithium-oxygen batteries have attracted considerable attention in the past several years due to their ultra-high theoretical energy density. However, there are still many serious issues that must be addressed before considering practical applications, including the sluggish oxygen redox kinetics, the limited capacity far from the theoretical value, and the poor cycle stability. This study proposes a surface modification strategy that can enhance the catalytic activity by loading Fe3C particles on carbon fibers, and the microstructure of Fe3C particle-modified carbon fibers is studied by multiple materials characterization methods. Experiments and density functional theory (DFT) calculations show that the discharge products on the Fe3C carbon fiber (Fe3C-CF) cathode are mainly Li2-xO2. Fe3C-CF exhibits high catalytic ability based on its promotion of the formation/decomposition processes of Li2-xO2. Consequently, the well-designed electrode catalyst exhibits a large specific capacity of 17,653.1 mAh g-1 and an excellent cyclability of 263 cycles at a current of 200 mA g-1.

Magnetically Tunable Adhesion of Magnetoactive Elastomers' Surface Covered with Two-Level Newt-Inspired Microstructures.

As one of the new intelligent materials, controllable bionic adhesive materials have great application prospects in many fields, such as wearable electronic devices, wall climbing robot systems, and biomedical engineering. Inspired by the microstructure of the newt pad's surface, this paper reports a bionic adhesive surface material with controllable adhesion on dry, wet acrylic, and iron sheet surfaces. The material is prepared by mixing the PDMS matrix with micron carbonyl iron powders (CIPs) and then pouring the mixture into a female mold prepared by Photo-curing 3D Printing for curing. As the mold interior is designed with a two-level microstructure array, the material's surface not only coated a regular hexagonal column array with a side length of 250 µm and a height of 100 µm but also covered seven dome structures with a diameter of 70 µm on each column. In what follows, the adhesion force of the proposed materials contacted three different surfaces are tested with/without magnetic fields. The experimental results show that the MAEs covered with two-level bionic structures(2L-MAE) reported in this paper exhibit a stronger initial adhesion in the three types of surfaces compared to the normal one. Besides, we also found that the magnetic field will noticeably affect their adhesion performance. Generally, the 2L-MAE's adhesion will increase with the external magnetic field. When the contact surface is an iron sheet, the material adhesion will be reduced by the magnetic field.

Clinical Effect of Free Gingival Grafts on the Increase in Keratinized Mucosa Width at the Buccal Aspect of Implants in Adjacent Mandibular Molars: A Retrospective Study.

The aim of this retrospective study was to evaluate the effect of free gingival grafts (FGGs) at adjacent mandibular molar implants and to compare the clinical outcomes between the first molar (M1) and second molar (M2) sites. Twenty-one patients with 44 implants were included. At the 3-year follow-up, the mean increase in the keratinized mucosa width (KMW) was 2.35 ± 1.33 mm, and the mean KMW shrinkage rate was 58% ± 23%. M1 sites showed a significantly greater increase of KMW and less graft shrinkage than M2 sites (M1: 2.87 ± 1.40 mm and 49% ± 24%, M2: 1.83 ± 1.06 mm and 66% ± 19%, P < .05). The results show that using FGG to increase KMW in mandibular molar implants was a predictable treatment method, and M1 sites were associated with a greater KMW increase than M2 sites.

Three-dimensional facial esthetics-driven computer-assisted osteotomy and implant placement for immediate restoration of a failing dentition with a protruded maxilla.

The rehabilitation of facial esthetics when transitioning from a failing dentition in a patient with maxillary protrusion is challenging. This clinical report described such a patient treated with an immediate cross-arch implant-supported fixed prosthesis. The ideal virtual upper lip position was used to predict the sagittal and vertical position of the restoration. A stackable device was fabricated to guide the osteotomy and implant placement.

Patient-reported outcome measures and clinical outcomes following peri-implant vestibuloplasty with a free gingival graft versus xenogeneic collagen matrix: a comparative prospective clinical study.

BACKGROUND: The objective of this study was to compare patient-reported outcome measures (PROMs) and clinical outcomes after augmentation with xenogeneic collagen matrix (XCM) or free gingival graft (FGG) during different postoperative phases. METHODS: Forty-two patients (21 per group) with keratinized mucosa width (KMW) of < 2 mm at buccal implant sites in the posterior mandible were enrolled. All underwent vestibuloplasty and were allocated to either FGG (control) or XCM (test) group. Intraoperative morbidity of pain, stress, nausea, tolerance to time, and acceptance of surgery were evaluated immediately after surgery. The severity and duration of subjective pain, swelling, and bleeding were compared within a 2-week postoperative period. The willingness to retreat and satisfaction were assessed at 6 months. All PROMs were obtained using questionnaires and visual analog scales. The buccal KMW and other peri-implant parameters were also evaluated. RESULTS: No significant between-group differences were observed in PROMs immediately after surgery, except acceptance of surgery (0, 0-30.0 vs. 30, 0-50.0, p = 0.025). At 2 weeks, pain severity (46.7 ± 25.9 vs 61.9 ± 20.2, p = 0.040) and duration (5.52 ± 3.57 vs 8.48 ± 2.80, p = 0.005) were significantly lower in the test group, and pain perception during speaking and chewing was significantly higher for FGG, with no significant between-group differences in swelling and bleeding. At 6 months, the test group showed a higher willingness to retreat (76% vs 43%, p = 0.021); however, satisfaction with treatment outcomes was similar in both groups. At 6 months, the gain of KMW was significantly higher in FGG than in XCM (XCM: 1.57 ± 1.69 mm, FGG: 2.68 ± 1.80 mm, p = 0.003). Other peri-implant parameters did not show significant differences. CONCLUSIONS: Within the limitation of the present nonrandomized study, XCM demonstrated more positive PROMs than FGG during different postoperative phases, mainly for less pain perception during the early healing stage, but was inferior to FGG in terms of gain of KMW. For KMW augmentation in the posterior mandible, XCM may be indicated when patients can bear little pain. CLINICAL TRIAL REGISTRATION: ChiCTR1900022575 , date of registration: 17/4/2019, retrospectively registered.

Occurrence and distribution of phthalate esters in freshwater aquaculture fish ponds in Pearl River Delta, China.

The concentrations, congener profiles and spatial distribution of 13 phthalate esters (PAEs) in the freshwater fish ponds in the Pearl River Delta (PRD) region were investigated in water and sediment samples collect from 22 sites during Jul. 2016-Sept. 2017. The di-2-ethylhexyl phthalate (DEHP) was the predominant compounds in both water and sediment samples, accounting for 70.1% and 66.1% of ∑PAEs, respectively. The DEHP concentrations in the water samples collected from the sites of Zhongshan (35.7 µg/L), Jingmen (17.3 µg/L) and Nanhai (14.2 µg/L) were higher than that collected from other sampling sites (p <0.05), and exceed the Chinese environmental quality standards for surface water (DEHP, 8.00 µg/L). The concentrations of ΣPAEs (mean and median were 11.8 mg/kg dw and 7.95 mg/kg dw) in sediment was higher than that in sediment of river and estuary in the PRD region (p <0.05). The median concentrations of DEHP and di-n-butyl phthalate (DBP) exceeded recommend environmental risk limit (ERL) that posed a potential risk to the aquaculture fish pond environment in the PRD.

Non-small cell lung cancer: Spectral computed tomography quantitative parameters for preoperative diagnosis of metastatic lymph nodes.

OBJECTIVE: To investigate the application value of spectral computed tomography (CT)quantitative parameters for preoperative diagnosis of metastatic lymph nodes in patients with non-small cell lung cancer (NSLC). METHODS: 84 patients with suspected lung cancer who underwent chest dual-phase enhanced scan with gemstone spectral CT imaging (GSI) mode were selected. GSI quantitative parameters including normalized iodine concentrations (NIC), water concentration, slope of the spectral Hounsfield unit curve (λHU) were measured. The two-sample t test was used to statistically compare these quantitative parameters. Receiver operating characteristic (ROC) curves were drawn to establish the optimal threshold values. RESULTS: A total of 144 lymph nodes were included, with 48 metastatic lymph nodes and 96 non-metastatic lymph nodes. The slope of the spectral Hounsfeld unit curve (λHU) measured during both arterial and venous phases were signifcantly higher in metastatic than in benign lymph nodes (P<0.05). The area under the ROC curve (AUC=0.951) of λHU of the arterial phase (AP) was the largest. When the optimal threshold values of λHU was 2.75, the sensitivity, specificity, and overall accuracy in the diagnosis of metastatic lymph nodes were 88.2%, 88.4%, 87.0%, respectively. CONCLUSION: Conventional CT diagnostic criteria established in accordance with size (lymph node maximal short axis diameter ≥10mm) as the basis for judging metastatic lymph node. In quantitative assessment using spectral CT imaging, quantitative parameters showed higher accuracy than qualitative assessment of conventional CT based on the size for preoperative diagnosis of metastatic lymph nodes.

Evaluation of stenosis severity of coronary calcified lesions using transluminal attenuation gradient: clinical application of 320-row volume CT.

BACKGROUND: The aim of this study was to evaluate the accuracy of transluminal attenuation gradient (TAG) in diagnosing the stenosis degree of difficult lesions to accurately assess the degree of luminal stenosis using coronary computed tomography angiography (CCTA). METHODS: A total of 130 patients consecutively received CCTA and coronary angiography (CAG). The average transluminal Hounsfield units (HU) of the regions of interest were consecutively measured at an interval of 5 mm from the ostium to the distal level, followed by the calculation of TAG. The diagnostic performance of CCTA, TAG and CCTA+TAG for the stenosis degree of coronary calcified lesions and their reclassification for stenosis degree were analyzed, especially for calcified lesions. RESULTS: Compared with CAG, the TAG in CCTA was consistent with the largest stenosis degree of each blood vessel. TAG improved the accuracy of CCTA in the diagnosis of calcified lesions (P<0.0001). When threshold was ≤-6.9 HU/10 mm, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CCTA+TAG in the diagnosis of coronary calcified lesions were 90.26%, 95.45%, 98.58% and 73.68%. TAG for calcified lesions had moderate sensitivity (86.61%; 95% CI: 81.8-90.5%) and high specificity (91.20%; 95% CI: 84.8-95.5%). In addition, TAG can help to improve the reclassification of CCTA for coronary stenosis degree, especially for calcified lesions (NRI=0.127, P=0.045). CONCLUSIONS: TAG can help to improve the diagnostic performance of CCTA for the stenosis degree of lesions, and it may also help to improve the reclassification of the stenosis degree of calcified lesions.

[GSI Quantitative Parameters: Preoperative Diagnosis of Metastasis Lymph Nodes in Lung Cancer].

BACKGROUND: Mediastinal involvement in lung cancer is an important prognostic factor affecting survival, and accurate staging of the mediastinum lymph node correctly identifies patients who can benefit the most from surgery. The aim of this study is to investigate the value of dual-energy spectral computed tomography (DEsCT) imaging in differentiating metastatic from non-metastatic lymph nodes in lung cancer. METHODS: Forty-eight patients with non-small cell lung cancer (NSCLC) underwent arterial (AP) and portal venous (PP) phase contrast-enhanced DEsCT imaging followed by surgical treatment. gemstone spectral imaging (GSI) data images were reconstructed and transmitted to an offline workstation. GSI quantitative parameters, including lymph-node size, CT value, IC, water concentration, and spectral curve. Differences were tested for statistical significance using the two-sample t test. ROC analysis was performed to assess diagnostic performance. RESULTS: The mean short-axis diameter of metastatic LNs, slope of the spectral Hounsfield unit curve (λHU), normalized iodine concentration measured during, and both AP and PP were significantly higher in metastatic lymph node than that in benign lymph nodes. The best parameter for detecting metastatic lymph nodes was AP λHU when a threshold λHU of 2.75 was used; sensitivity, specificity, and accuracy were 88.2%, 88.4%, and 87.0%, respectively. CONCLUSIONS: Quantitative assessment with gemstone spectral imaging quantitative parameters showed higher accuracy than the qualitative assessment of conventional CT imaging features for the preoperative diagnosis of metastatic lymph nodes in patients with lung cancer.
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